Let’s decode the planet’s nitrogen problem

Through fertilizers, fossil fuels and agriculture, the planet’s nitrogen system has been in supercharge mode since the Industrial Revolution. This means more air pollution, burdened ecosystems and excess greenhouse gas emissions.

Scientists are working hard to combat the fallout, and it seems tiny chemical isotopes may come in with the assist.

Isotopes are like tiny barcodes that scientists use to track the source of all that nitrogen and where it ends up. Each isotope acts like a fingerprint that helps researchers determine which pollution comes from cars, factories, forests or soil.

The recent review published in Nitrogen Cycling shows that forests actively modify incoming nitrogen rather than simply letting it fall straight through.

It also shows plants may use more nitrate than we thought and that processing nitrogen takes up a large amount of plants’ energy.

By connecting climate models and isotope tracking, scientists aim to better predict how nitrogen pollution will impact our warming world, and how we might ultimately curb it.

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Quiet please … proteins are sharing
secrets

Proteins, one of the most studied and complex molecules in biology, are the worker bees of a cell. They play an essential role in most biological systems and are responsible for most cellular functions. So, scientists thought they had a pretty good handle on the bonds that hold proteins together, but it seems they missed a few.

A new study published in Communications Chemistry reveals four brand-new types of chemical connections in proteins. Specifically, these connections involve nitrogen, oxygen and sulfur and are called NOS bonds.

The connections were discovered by reanalyzing already explored data of 86,000 protein structures and searching for patterns using an AI tool called SimplifiedBondfinder.

The search highlighted 69, previously missed NOS bonds, including some involving the amino acids glycine and arginine

These connections could play important roles in how proteins respond to changes in the body like oxidative stress or why they behave in certain ways not previously understood.

This recent find could help in designing new drugs or custom proteins. Knowing about these new types of bonds could help to build better, more effective molecules.

Sometimes looking back is the key to moving forward.

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